Refinement & validation of rectal wall dose volume objectives for prostate hypofractionation in 20 fractions
نویسندگان
چکیده
منابع مشابه
The effect of Rectal Retractor, a rectal protector on rectal dose in radical prostate radiotherapy
Introduction: The close proximity of the rectum tissue to the prostate gland results in rectal toxicity during prostate radiotherapy. Rectal Retractor (RR) is a rectal displacement technique that inserts into the rectum, as a result, the lateral and dorsal part of the rectal wall push away from high dose areas. The aim of this study was to investigate the dosimetric consequence...
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PURPOSE To compare the fits of normal-tissue complication probability (NTCP) models based on rectal dose-wall histograms (DWHs) vs. dose-volume histograms (DVHs) when the two are used to analyze a common set of late rectal toxicity data. METHODS AND MATERIALS Data were analyzed from 128 prostate cancer patients treated with 3-dimensional conformal radiotherapy (3D-CRT) at The University of Te...
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Background: In intracavitary brachytherapy for gynecological cancers, various techniques are used to locate the anterior rectal wall nearest to the sources but there is no consensus on the best method to do so. This study aimed to compare a technique used routinely in some centers that employs a wire marker to locate the position of the maximum rectal dose point, versus the method recommended b...
متن کاملPreoperative radiotherapy for rectal cancer: hypofractionation with multiple fractions (15-25 Gy).
Preoperative radiotherapy lowers local recurrence rates after rectal cancer surgery, as seen in several randomised trials. Postoperative radiotherapy is also effective, although a higher radiation dose is required. In addition, preoperative, but not postoperative (unless combined with chemotherapy) radiotherapy also improves survival slightly. Since the toxicity profile also favours preoperativ...
متن کاملProstate IMRT: Two-dimensional model of rectal NTCP employing the variability of rectal motion and rectum wall thickness
Background: In order to improve the evaluation of possible rectal toxicity based on the rectal normal tissue complication probability (NTCP), we consider the fractional dependence of the NTCP on the wall thickness (tW) and rectal displacement (RM). Materials and Methods: The two-dimensional NTCP model (NTCP2D) was developed using radiotherapy plans of ten randomly selected patients with prostat...
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ژورنال
عنوان ژورنال: Clinical and Translational Radiation Oncology
سال: 2020
ISSN: 2405-6308
DOI: 10.1016/j.ctro.2020.01.006